Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Implantable cardioverter-defibrillator in cardiac sarcoidosis: A propensity-score matched analysis.

Current problems in cardiology·2026

Same author

Comparison of P2Y<sub>12</sub> inhibitors vs. aspirin monotherapy following dual antiplatelet therapy in patients after percutaneous coronary intervention: a systematic review and meta-analysis.

Archives of medical sciences. Atherosclerotic diseases·2026

Same author

Efficacy and safety of intralesional versus intracoronary administration of glycoprotein IIb/IIIa inhibitors during percutaneous coronary intervention for acute coronary syndromes: a meta-analysis of randomized controlled trials.

Coronary artery disease·2026

Same author

Decompression with or without Duraplasty for Chiari I and Syringomyelia.

The New England journal of medicine·2026

Same author

The silent epidemic: Cardiovascular mortality among patients with thyroid disorders-Insights from CDC-WONDER database (1999-2023).

Journal of investigative medicine : the official publication of the American Federation for Clinical Research·2026

Same author

Cardiovascular and Renal Outcomes of GLP-1 Receptor Agonists in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.

European heart journal. Quality of care & clinical outcomes·2026

Same journal

Corrigendum to Temporary Pacemaker in a Pediatric Guillain-Barré Case With Life-Threatening Bradyarrhythmia Pediatr Neurol 177 (2026) 109-110. doi: 10.1016/j.pediatrneurol.2026.01.015.

Pediatric neurology·2026

Same journal

Clinical Symptoms in Late Infantile and Juvenile Onset Neuronal Ceroid Lipofuscinosis Type 7 (CLN7 Disease).

Pediatric neurology·2026

Same journal

Examining Epilepsy in Angelman Syndrome: Insights From Caregiver-Reported Data in the Linking Angelman and Dup15q Data for Expanded Research Database.

Pediatric neurology·2026

Same journal

Impact of Postpandemic Pediatric Infection Rebound on Febrile Seizures: A Nationwide Cohort Study, 2013-2023.

Pediatric neurology·2026

Same journal

The Hidden Cost of Developmental and Epileptic Encephalopathy in Australia: Caregiver Quality of Life, Sleep, Depression, and Workforce Participation.

Pediatric neurology·2026

Same journal

A Novel Neonatal Brain Injury Score for Infants With Congenital Diaphragmatic Hernia.

Pediatric neurology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 9, 2025

A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice

A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice

Published on: June 22, 2022

Bilateral Rasmussen Encephalitis: Good Outcome Following Hemispherotomy.

Noah Trapp¹, Dominic O Co², Susan Rebsamen³

¹Section of Pediatric Neurology, Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

Pediatric Neurology

|December 2, 2023

Summary

This summary is machine-generated.

Bilateral Rasmussen encephalitis, a rare condition, can be treated with hemispherotomy, offering improved quality of life. This surgical approach shows promise even in severe, bilateral cases, challenging previous assumptions.

Keywords:

Bilateral Rasmussen Chronic encephalitis Epilepsy surgery Rasmussen encephalitis Rasmussen syndrome

More Related Videos

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Published on: August 16, 2024

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

Related Experiment Videos

Last Updated: Jul 9, 2025

A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice

A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice

Published on: June 22, 2022

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Published on: August 16, 2024

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

Area of Science:

Neuroscience
Pediatric Neurology
Epileptology

Background:

Rasmussen encephalitis is a rare, severe neurological disorder typically affecting one brain hemisphere.
Bilateral cases are exceptionally rare, often associated with poor outcomes and limited treatment options.
Surgical interventions like hemispherotomy are frequently considered contraindicated in bilateral presentations.

Observation:

A 4-year-old male presented with escalating focal seizures and progressive neurological deficits indicative of bilateral Rasmussen encephalitis.
Despite initial transient responses to immunosuppressants, the patient developed super-refractory status epilepticus.
Histopathological examination confirmed bilateral involvement of the disease.

Findings:

The patient underwent a right functional hemispherotomy 4.5 years after symptom onset.
Post-surgery, the patient achieved an Engel 1D outcome classification, signifying excellent seizure control.
A 2.5-year follow-up revealed a substantially improved quality of life.

Implications:

This case challenges the contraindication of hemispherotomy in bilateral Rasmussen encephalitis.
Favorable outcomes may be achievable with hemispherotomy when seizures remain predominantly unihemispheric.
Highlights the potential of targeted surgical intervention in refractory, bilateral neurological conditions.