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Supporting evidence-based rotavirus vaccine introduction decision-making and implementation: Lessons from 8
Mary Carol Jennings1, Molly Sauer1, Chloe Manchester2
1Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA; International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.
Vaccine
|December 2, 2023
Summary
The Rotavirus Accelerated Vaccine Introduction Network (RAVIN) supported eight countries in introducing rotavirus vaccines (RVV). Five countries successfully introduced RVV, reducing risks for millions of children.
Area of Science:
- Global Health
- Vaccinology
- Public Health Policy
Background:
- Rotavirus vaccines (RVV) recommended by WHO in 2009 had low uptake by 2015, leaving millions of children vulnerable.
- The Rotavirus Accelerated Vaccine Introduction Network (RAVIN) was established in 2016 to aid RVV introduction in Gavi-eligible countries.
Purpose of the Study:
- To report on the RAVIN approach to supporting rotavirus vaccine introduction.
- To analyze country experiences and lessons learned for future vaccine introductions.
Main Methods:
- RAVIN provided technical assistance and supported evidence-based decision-making for RVV introduction in eight focus countries.
- The project facilitated preparation, implementation, and multilateral coordination from 2016 to 2020.
Main Results:
- Five of the eight RAVIN focus countries successfully introduced rotavirus vaccines into their routine immunization programs by September 2020.
- The project navigated an evolving RVV product landscape and addressed country-specific needs.
Conclusions:
- The RAVIN initiative demonstrated a successful model for accelerating rotavirus vaccine introduction in resource-limited settings.
- Key lessons learned from RAVIN can inform future global new vaccine introduction efforts.

