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Related Concept Videos

Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
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Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Investigation of Disease Outbreaks01:23

Investigation of Disease Outbreaks

Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
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Inflammatory Bowel Disease IV: Clinical Manifestations

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Related Experiment Video

Updated: May 10, 2026

Enteric Bacterial Invasion Of Intestinal Epithelial Cells In Vitro Is Dramatically Enhanced Using a Vertical Diffusion Chamber Model
10:52

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Published on: October 22, 2013

Campylobacter enteritis: clinical and epidemiologic features.

M J Blaser, I D Berkowitz, F M LaForce

    Annals of Internal Medicine
    |August 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Campylobacter fetus subspecies jejuni causes diarrhea in humans. This enteric pathogen was found in 5% of patients and their symptomatic contacts, suggesting its role in infectious diarrhea.

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    Area of Science:

    • Microbiology
    • Infectious Diseases
    • Gastroenterology

    Background:

    • Campylobacter fetus subspecies jejuni (C. fetus ssp. jejuni) is increasingly recognized as a cause of human diarrheal disease.
    • Understanding its prevalence and clinical significance is crucial for public health.
    • This study aimed to assess the importance of C. fetus ssp. jejuni as an enteric pathogen.

    Observation:

    • A prospective study involved 514 patients presenting with diarrhea.
    • C. fetus ssp. jejuni was isolated from 5% of these patients.
    • The pathogen was also detected in symptomatic household contacts, but rarely in asymptomatic individuals.

    Findings:

    • Fecal cultures yielded C. fetus ssp. jejuni in 26 of 514 diarrheal patients (5%).
    • Seven of 11 symptomatic household contacts tested positive, indicating potential person-to-person transmission.
    • Elevated specific IgG titers were observed in most infected patients, confirming an immune response.

    Implications:

    • C. fetus ssp. jejuni is a significant enteric pathogen contributing to human gastroenteritis.
    • The findings highlight the importance of considering C. fetus ssp. jejuni in the differential diagnosis of infectious diarrhea.
    • Further research into transmission routes and effective treatments is warranted.