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Poisoning associated with potassium.

A K Chaturvedi, N G Rao, M D Moon

    Human Toxicology
    |December 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    This case study details a fatal suicidal poisoning using concentrated potassium chloride intravenously. Post-mortem analysis confirmed lethal potassium levels, highlighting the challenges in diagnosing such electrolyte-induced deaths.

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    Area of Science:

    • Forensic toxicology
    • Clinical pathology
    • Cardiovascular physiology

    Background:

    • Describes a fatal case of suicidal poisoning via concentrated potassium chloride (K+Cl-) administered intravenously.
    • Highlights the challenges in forensic investigations of deaths potentially caused by electrolyte imbalances.

    Observation:

    • A 30-year-old female health professional was found deceased with an intravenous needle and syringe containing a concentrated K+ solution.
    • Autopsy revealed pulmonary edema and congestion; routine toxicology excluded drug overdose.
    • The syringe contained a highly concentrated K+ solution (1468 mmol/l), with elevated K+ levels in post-mortem plasma (54 mmol/l) and vitreous humor (9.2 mmol/l).

    Findings:

    • The concentrated K+ solution in the syringe was identified as the likely cause of death.

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  • Post-mortem electrolyte levels in plasma and vitreous humor, while elevated, may not definitively confirm K+ poisoning due to potential post-mortem shifts.
  • The evidence linking the K+ solution to the death was circumstantial.

    • Implications:

    • This case underscores the importance of considering non-traditional toxic agents in forensic investigations.
    • It suggests that elevated post-mortem potassium levels alone may be insufficient evidence for K+ toxicity, requiring careful interpretation alongside circumstantial evidence.
    • The findings emphasize the need for comprehensive toxicological screening and meticulous examination of scene evidence in suspected poisoning cases.