Related Experiment Video

Updated: Jul 9, 2025

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
06:04

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

Published on: February 24, 2023

2.4K

Chest imaging classification in Mycoplasma pneumoniae pneumonia is associated with its clinical features and outcomes

Xia Huang1, Haiyan Gu1, Ruxi Wu1

  • 1Department of Respiratory Medicine, Children's Hospital of Nanjing Medical University, Nanjing, 210008, China.

Respiratory Medicine
|December 3, 2023
PubMed

Insights

Chest imaging findings in Mycoplasma pneumoniae pneumonia (MPP) correlate with clinical severity and outcomes. Consolidation/atelectasis indicates more severe disease, while mosaic patterns suggest milder cases in children.

Area of Science:

  • Pediatric Pulmonology
  • Infectious Diseases
  • Radiology

Background:

  • Mycoplasma pneumoniae pneumonia (MPP) presents with diverse imaging findings.
  • Limited research exists on the correlation between MPP imaging classifications and clinical outcomes.

Purpose of the Study:

  • To prospectively examine the association between chest imaging classifications of MPP and its clinical features and outcomes in children.

Main Methods:

  • 1,401 hospitalized children with MPP were analyzed.
  • Imaging findings were classified using X-ray (bronchopneumonia, consolidation/atelectasis) and CT (bronchopneumonia, consolidation/atelectasis, bronchiolitis, mosaic pattern).
  • Clinical data and outcomes were prospectively collected and analyzed.

Main Results:

  • Bronchopneumonia was the most frequent finding (59.6%).
  • Consolidation/atelectasis represented the most severe group, associated with significant clinical abnormalities, prolonged fever and hospitalization, increased costs, and higher risks of refractory MPP, necrotizing pneumonia, and bronchiolitis obliterans (BO).
  • Mosaic patterns were linked to allergic/younger patients with wheezing, mild symptoms, and favorable outcomes.

Conclusions:

  • Distinct imaging classifications of MPP correlate with specific clinical features and patient outcomes.
  • An imaging-based classification system for MPP holds significant clinical value for predicting disease course and guiding management.
Abstract

Keywords:
Chest imagingClassificationClinical featuresMycoplasma pneumoniaOutcomes

More Related Videos

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia08:05

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

14.2K
Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling08:25

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling

Published on: April 7, 2015

9.1K

Related Concept Videos

Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
239
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
245
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
285
Pneumonia IV: Management01:28

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
333
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
336
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
292