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Related Concept Videos

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Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
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The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
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Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
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Vomiting is a complex physiological response to expel harmful or irritating substances from the body. It's a defensive mechanism triggered by stimuli like poisons, microbial toxins, cytotoxic drugs, and mechanical abdominal distension. The process is centrally coordinated by the vomiting (or emetic) center located in the medulla of the brainstem. This area, rich in muscarinic M1, histamine H1, neurokinin 1 (NK1), and serotonin 5-HT3 receptors, coordinates the act of vomiting through...
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Gastrointestinal Motility Disorders

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Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
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Related Experiment Video

Updated: Jul 9, 2025

A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis
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Infantile colic.

Amy A Gelfand1

  • 1Child & Adolescent Headache Program, Department of Neurology, University of California San Francisco, San Francisco, CA, United States.

Handbook of Clinical Neurology
|December 3, 2023
PubMed
Summary
This summary is machine-generated.

Infant colic, marked by intense crying, is linked to migraine. This association appears in both children with migraine and their mothers, suggesting a potential genetic or shared predisposition.

Keywords:
Infant colicMigraine

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Area of Science:

  • Pediatrics
  • Neurology
  • Genetics

Background:

  • Infant colic involves excessive crying in healthy infants, peaking around 5-6 weeks.
  • Colic exhibits a developmental and circadian pattern, with increased crying in the evenings.
  • Infant colic is considered an amplified form of typical infant crying behavior.

Approach:

  • The study reviews evidence associating infant colic with migraine.
  • It examines the prevalence of colic in children with migraine.
  • It also investigates the likelihood of colic in infants born to mothers with migraine.

Key Points:

  • There is substantial evidence linking infant colic and migraine.
  • Children with a history of migraine are more likely to have experienced colic.
  • Mothers with migraine, especially those with frequent headaches, have a higher incidence of infants with colic.

Conclusions:

  • The association between infant colic and migraine is significant.
  • Clinicians should inform pregnant women with migraine about the possibility of infant colic.
  • Recognizing this link aids in diagnosing migraine in children and adolescents with recurrent headaches.