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Pseudoaneurysm of mitral-aortic intervalvular fibrosa with rupture: a case report
Kosuke Nakata1,2, Shuji Moriyama3, Jun Takaki4
1Department of Cardiovascular Surgery, Kumamoto Rosai Hospital, 1670 Takehara-Machi, Yatsushiro, Kumamoto, 866-8533, Japan. nakata.kosuke@kuh.kumamoto-u.ac.jp.
Background:
Mitral-aortic intervalvular fibrosa (MAIVF) is a fibrous region connecting the anterior mitral leaflet (AML) and aortic valve. Pseudoaneurysm of the MAIVF is a rare condition that has been reported as a sequela of infective endocarditis (IE) and surgical trauma. Here, we report a case of a ruptured pseudoaneurysm of the MAIVF, along with some literature reviews.
Case Presentation:
A 65-year-old man diagnosed with moderate aortic regurgitation five years previously had a fever of unknown origin. He suddenly developed headache and apraxia and was transported to our hospital. He was diagnosed with intracranial hemorrhage and admitted. One week after admission, echocardiography revealed aorto-mitral discontinuity and protrusion with severe regurgitant flow from left ventricular outflow tract to the left atrium. The AML was suspected to have ruptured. However, intraoperatively, the AML structure was preserved. A ruptured pseudoaneurysm of the MAIVF was also observed. Therefore, we successfully performed pseudoaneurysm repair using a bovine pericardial patch, aortic valve replacement, and mitral annuloplasty.
Conclusions:
P-MAIVF is a rare but potentially life-threatening complication of IE, for which timely diagnosis and prompt appropriate therapeutic intervention are required. In the present case, although neither obvious active IE nor history of previous IE could be identified, healed IE was considered based on the clinical course. The patient had intracranial hemorrhage (ICH) with well-controlled heart failure and underwent elective surgical repair more than one month after the onset of ICH, while the clinical course after the surgical procedure was uneventful.
Insights
A ruptured pseudoaneurysm of the mitral-aortic intervalvular fibrosa (MAIVF) is a rare, life-threatening complication, often linked to healed infective endocarditis. Prompt diagnosis and surgical repair are crucial for successful outcomes.
Area of Science:
- Cardiology
- Cardiac Surgery
- Cardiovascular Pathology
Background:
- Mitral-aortic intervalvular fibrosa (MAIVF) is a connective fibrous tissue between the anterior mitral leaflet and aortic valve.
- Pseudoaneurysm of the MAIVF is an uncommon condition, frequently associated with infective endocarditis (IE) or surgical trauma.
- Ruptured MAIVF pseudoaneurysms pose a significant risk of cardiovascular compromise.
Purpose of the Study:
- To report a rare case of a ruptured pseudoaneurysm of the MAIVF.
- To review existing literature on MAIVF pseudoaneurysms.
- To highlight the importance of timely diagnosis and intervention for this condition.
Main Methods:
- A 65-year-old male with moderate aortic regurgitation presented with fever, headache, and apraxia, diagnosed with intracranial hemorrhage.
- Echocardiography revealed aorto-mitral discontinuity and severe regurgitation, initially suspected as AML rupture.
- Intraoperative findings confirmed a ruptured MAIVF pseudoaneurysm, necessitating repair with a bovine pericardial patch, aortic valve replacement, and mitral annuloplasty.
Main Results:
- The patient presented with symptoms of intracranial hemorrhage and was diagnosed with a ruptured MAIVF pseudoaneurysm.
- Surgical repair involved a bovine pericardial patch, aortic valve replacement, and mitral annuloplasty.
- The patient's condition was managed successfully, with uneventful recovery following elective surgical repair.
Conclusions:
- Pseudoaneurysm of the MAIVF (P-MAIVF) is a rare but potentially fatal complication, often linked to healed infective endocarditis.
- Timely diagnosis and prompt, appropriate therapeutic intervention are essential for managing ruptured MAIVF pseudoaneurysms.
- This case underscores the need for vigilance in diagnosing and treating MAIVF pseudoaneurysms, even in the absence of active IE.
Related Concept Videos
Mitral Valve Prolapse I: Introduction
Mitral Regurgitation I: Introduction
Mitral Stenosis I: Introduction
Aneurysm I: Introduction
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Aneurysm III: Interprofessional Care

