Related Experiment Video

Updated: Jun 27, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

17.6K

Sonographic cortical bone thickness measurement: can it predict bone mineral density in the pediatric population?

Uğur Ufuk Işın1, Emin Çakmakçı2, Ayşe Derya Buluş3

  • 1University of Health Sciences Türkiye, Atatürk Sanatorium Training and Research Hospital, Clinic of Pediatrics, Ankara, Türkiye

Diagnostic and Interventional Radiology (Ankara, Turkey)
|December 4, 2023
PubMed

Insights

Sonographic cortical bone thickness (CoT) measurements in children do not correlate with bone mineral density (BMD). Therefore, CoT is not a reliable indicator for assessing pediatric osteoporosis.

Area of Science:

  • Pediatric Radiology
  • Orthopedics
  • Bone Health

Background:

  • Pediatric osteoporosis diagnosis relies on bone mineral density (BMD) measurements.
  • Non-invasive methods for assessing pediatric bone health are needed.
  • Cortical bone thickness (CoT) shows promise in adult bone assessment.

Purpose of the Study:

  • To evaluate sonographic cortical bone thickness (CoT) as a potential screening tool for pediatric osteoporosis.
  • To determine the correlation between CoT and bone mineral density (BMD) in children.

Main Methods:

  • Prospective study involving 41 osteopenic/osteoporotic children and 52 healthy controls.
  • Measured radius (R-CoT), tibial (T-CoT), and second metatarsal (M-CoT) cortical thickness using B-mode ultrasound.
  • Compared CoT values between groups and correlated with BMD T-scores.

Main Results:

  • No significant differences in R-CoT, T-CoT, or M-CoT between patient and control groups.
  • No significant correlations were found between BMD T-scores and any of the measured CoT values (R-CoT, T-CoT, M-CoT).

Conclusions:

  • Sonographic CoT measurements do not correlate with BMD in the pediatric population.
  • Cortical bone thickness measured by ultrasound is not a suitable indicator for assessing BMD or diagnosing osteoporosis in children.
Abstract

Keywords:
Osteoporosisbonechildrencorticaldensitythicknessultrasonography

More Related Videos

Assessment of Bone Fracture Healing Using Micro-Computed Tomography12:04

Assessment of Bone Fracture Healing Using Micro-Computed Tomography

Published on: December 9, 2022

1.9K
Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population09:02

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population

Published on: January 31, 2025

493

Related Concept Videos

Bone Structure01:55

Bone Structure

Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
Ultrasonography01:17

Ultrasonography

Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called a...
Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Spongy Bone01:09

Spongy Bone

All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...