Pathogenesis and preventions of denture stomatitis

Area of Science:

• Oral Medicine
• Infectious Diseases
• Biomaterials

Background:

• Denture stomatitis (DS) is a prevalent oral mucosal lesion affecting denture wearers.
• Traditional treatments risk drug-resistant strains, necessitating alternative strategies.
• DS compromises oral health and requires effective management.

Purpose of the Study:

• To review emerging and alternative treatments for denture stomatitis.
• To explore natural ingredients, photodynamic therapy, and denture modification as DS therapies.
• To identify strategies for combating *Candida albicans* in DS.

Main Methods:

• Literature review of current and novel DS prevention and treatment modalities.
• Analysis of natural preparations, photodynamic therapy, and denture material modifications.
• Evaluation of combination therapies against *Candida albicans*.

Main Results:

• Natural ingredients offer safe, cost-effective, and less resistance-prone treatment options.
• Photodynamic therapy demonstrates potent antibacterial effects with convenience and safety.
• Denture modification with antibacterial agents presents a novel therapeutic avenue.

Conclusions:

• Emerging treatments like natural products and photodynamic therapy show promise for DS.
• Denture modification and combination therapies offer innovative strategies against *Candida albicans*.
• Future research should focus on these alternative approaches for effective DS management.