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Updated: Jul 9, 2025
Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
Feasibility of undersampled spiral trajectories in MREPT for fast conductivity imaging
Safa Özdemir1,2, Efe Ilicak1,2, Jascha Zapp1,2
1Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Purpose:
To investigate spiral-based imaging including trajectories with undersampling as a fast and robust alternative for phase-based magnetic resonance electrical properties tomography (MREPT) techniques.
Methods:
Spiral trajectories with various undersampling ratios were prescribed to acquire images from an experimental phantom and a healthy volunteer at 3T. The non-Cartesian acquisitions were reconstructed using SPIRiT, and conductivity maps were derived using phase-based cr-MREPT. The resulting maps were compared between different sampling trajectories. Additionally, a conductivity map was obtained using a Cartesian balanced SSFP acquisition from the volunteer to comparatively demonstrate the robustness of the proposed method.
Results:
The phantom and volunteer results illustrate the benefits of the spiral acquisitions. Specifically, undersampled spiral acquisitions display improved robustness against field inhomogeneity artifacts and lowered SD values with shortened readout times. Furthermore, average of conductivity values measured for the cerebrospinal fluid with the spiral acquisitions were 1.703 S/m, indicating a close agreement with the theoretical values of 1.794 S/m.
Conclusion:
A spiral-based acquisition framework for conductivity imaging with and without undersampling is presented. Overall, spiral-based acquisitions improved robustness against field inhomogeneity artifacts, while achieving whole head coverage with multiple averages in less than a minute.
