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Updated: Jul 9, 2025

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
Allergic bronchopulmonary aspergillosis manifested secondary to bacterial pleural empyema
Hiromu Kawano1, Keiko Kan-O1, Ayaka Egashira1
1Department of Respiratory Medicine, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Abstract:
A 54-year-old woman with no history of lung disease including bronchial asthma developed left bacterial pleural empyema due to the perforation of a lung abscess in the left lower lobe. Chest tube drainage and antibiotics improved the pleural empyema. Two months following discharge from the hospital, she developed a cough and left chest pain. Chest computed tomography revealed high-attenuation mucus plugs, atelectasis in the left lower lobe, and an increased peripheral blood eosinophil count. Bronchoscopy revealed a mucoid impaction in B8 of the left lower lobe, confirming the presence of Aspergillus fumigatus. A diagnosis of allergic bronchopulmonary aspergillosis was made, and treatment with oral prednisolone was initiated, resulting in the resolution of the mucus plugs and improvement of atelectasis.
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