Food intolerance in patients with oro-facial granulomatosis

The study was initiated to investigate the role of food intolerance in the aetiology of oro-facial granulomatosis. Firstly, retrospective data were examined in 85 patients and in 16 of them it was evident that a food or flavouring was provoking the disorder. In a second series, eight patients completed a very-low-allergen diet: seven individuals were found to be intolerant of certain foods, ingestion of which resulted in facial swelling. It is concluded that food intolerance is an aetiological factor in some patients with oro-facial granulomatosis.