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Racial difference in mortality among COVID-19 hospitalizations in California
Muni Rubens1,2, Venkataraghavan Ramamoorthy3, Anshul Saxena3
1Miami Cancer Institute, Baptist Health South Florida, Miami, FL, USA.
Insights
Hispanic COVID-19 patients in California experienced significantly higher in-hospital mortality and intensive care unit (ICU) admission rates compared to White patients. These findings highlight critical racial disparities in COVID-19 outcomes.
Area of Science:
- Public Health
- Epidemiology
- Health Disparities
Background:
- Racial disparities in US hospital outcomes are well-documented.
- COVID-19 has disproportionately affected minority populations.
Purpose of the Study:
- To investigate the association between race and in-hospital mortality among COVID-19 patients in California.
- To examine the association between race and intensive care unit (ICU) admission in COVID-19 patients.
Main Methods:
- Retrospective analysis of the California State Inpatient Database for 2020.
- Inclusion of COVID-19 hospitalizations for patients aged 18 years and older.
- Utilized Cox proportional hazards and logistic regression models to assess associations between race and outcomes.
Main Results:
- Analysis included 87,934 COVID-19 hospitalizations: Hispanic (56.5%), White (27.3%), Asian/Pacific Islander/Native American (9.9%), Black (6.3%).
- Hispanic patients showed higher mortality risk compared to White, Black, and Asian/Pacific Islander/Native American groups.
- Hispanic, Black, and Asian/Pacific Islander/Native American patients had significantly higher odds of ICU admission compared to White patients.
Conclusions:
- Significant racial disparities in COVID-19 mortality and ICU admission were observed in California.
- Hispanic individuals faced the most severe outcomes, with the highest mortality and ICU admission rates.
- Findings underscore the need for targeted interventions to address racial inequities in healthcare.
Abstract:
In the US, racial disparities in hospital outcomes are well documented. We explored whether race was associated with all-cause in-hospital mortality and intensive care unit (ICU) admission among COVID-19 patients in California. This was a retrospective analysis of California State Inpatient Database during 2020. Hospitalizations ≥ 18 years of age for COVID-19 were included. Cox proportional hazards with mixed effects were used for associations between race and in-hospital mortality. Logistic regression was used for the association between race and ICU admission. Among 87,934 COVID-19 hospitalizations, majority were Hispanics (56.5%), followed by White (27.3%), Asian, Pacific Islander, Native American (9.9%), and Black (6.3%). Cox regression showed higher mortality risk among Hispanics, compared to Whites (hazard ratio, 0.91; 95% CI 0.87-0.96), Blacks (hazard ratio, 0.87; 95% CI 0.79-0.94), and Asian, Pacific Islander, Native American (hazard ratio, 0.89; 95% CI 0.83-0.95). Logistic regression showed that the odds of ICU admission were significantly higher among Hispanics, compared to Whites (OR, 1.70; 95% CI 1.67-1.74), Blacks (OR, 1.70; 95% CI 1.64-1.78), and Asian, Pacific Islander, Native American (OR, 1.82; 95% CI 1.76-1.89). We found significant disparities in mortality among COVID-19 hospitalizations in California. Hispanics were the worst affected with the highest mortality and ICU admission rates.
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