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Assessment of Child Anthropometry in a Large Epidemiologic Study
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Birth outcomes and early growth patterns associated with age at adiposity rebound: the Ma'anshan birth cohort (MABC)

Jixing Zhou1,2,3,4, Yuzhu Teng1,2,3,4, Shanshan Zhang1,2,3,4

  • 1Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, 230032, China.

BMC Public Health
|December 4, 2023
PubMed

Insights

Early adiposity rebound (AR) is linked to higher obesity risk. Birth outcomes like low birth weight and rapid weight gain in infancy increase the risk of early AR in children.

Area of Science:

  • Pediatric Endocrinology
  • Developmental Pediatrics
  • Obesity Research

Background:

  • Early onset of adiposity rebound (AR) is a significant predictor of future obesity.
  • Understanding the factors influencing early AR is crucial for developing preventative strategies.

Purpose of the Study:

  • To investigate the association between birth outcomes and early physical growth patterns with the timing of adiposity rebound in children.
  • To identify key developmental trajectories linked to an increased risk of early AR.

Main Methods:

  • Utilized data from 2705 children in the Ma'anshan Birth Cohort (MABC).
  • Employed group-based trajectory modeling (GBTM) to identify physical growth patterns.
  • Analyzed body mass index (BMI), waist circumference, body fat, and rapid weight gain (RWG) in the first two years of life.

Main Results:

  • High BMI, waist circumference, and body fat trajectories before 72 months were associated with a greater risk of early AR.
  • Low birth weight, preterm birth, and small for gestational age increased the risk of early AR.
  • Rapid weight gain (RWG) and specific BMI trajectories (low or rising) in the first two years also elevated the risk of developing early AR.

Conclusions:

  • Children exhibiting high adiposity indicators or specific early growth patterns (RWG, certain BMI trajectories) face a higher likelihood of early adiposity rebound.
  • Identifying these early risk factors is essential for understanding and mitigating metabolic risks associated with childhood obesity.
Abstract

Keywords:
Adiposity reboundBMI trajectoryBirth outcomeChildrenRapid weight gain

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