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Updated: Jul 9, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Nosocomial infections in sickle cell anemia patients: Prevention through multi-disciplinary approach: A review
Emmanuel Ifeanyi Obeagu1, Getrude Uzoma Obeagu2, Callistus Akinleye Akinleye3
1Department of Medical Laboratory Science, Kampala International University, Uganda.
Abstract:
Sickle cell anemia (SCA), a hereditary blood disorder characterized by the presence of abnormal hemoglobin, poses a unique set of challenges for both patients and healthcare providers. One of the most pressing issues in the care of these individuals is the persistent threat of nosocomial infections, which are infections acquired during hospitalization. This abstract provides a concise overview of the ongoing challenge of nosocomial infections in SCA patients, highlighting the factors contributing to their vulnerability and the preventive measures in place. SCA patients face increased susceptibility to nosocomial infections due to their compromised immune systems, frequent hospitalizations, prolonged stays, and the need for invasive medical interventions. The emergence of multidrug-resistant pathogens further complicates the management of these infections. To address this challenge, healthcare facilities have implemented infection control protocols, vaccination strategies, and antimicrobial stewardship, emphasizing the importance of patient education. Recognizing the gravity of this issue and adopting comprehensive preventive measures is crucial to improving the quality of care and patient outcomes in this vulnerable population. Further research and ongoing efforts are essential to reducing the burden of nosocomial infections in SCA patients and enhancing their overall healthcare experience.
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