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Biomimetic urine flow control can preserve bladder function in patients with indwelling catheterization
Minrong Xu1, Wei Zhang, Lingxiang Sheng
1Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, China.
Medicine
|December 5, 2023
Summary
Biomimetic urine flow control (BUFC) may protect bladder function in patients with long-term indwelling catheters. This technology helped maintain stable urinary volume and flow rates, unlike standard catheterization.
Area of Science:
- Urology
- Biomedical Engineering
Background:
- Long-term indwelling catheterization can negatively impact bladder function.
- There is a need to explore methods to preserve bladder function during prolonged catheter use.
Purpose of the Study:
- To investigate the efficacy of biomimetic urine flow control (BUFC) in maintaining bladder function in patients with indwelling catheters.
- To compare bladder function parameters between patients using BUFC and those with unobstructed flow.
Main Methods:
- Retrospective, data-only cohort study.
- Inclusion of intensive care unit patients with indwelling catheters for over 30 days.
- Comparison of urodynamic monitoring data between a BUFC group (n=15) and an unobstructed group (n=15).
Main Results:
- The unobstructed group showed a continuous decline in urinary volume and maximal urinary flow rate.
- The BUFC group maintained stable urinary volume and maximal urinary flow rate.
- A statistically significant difference (P < .05) was observed between groups from day 20 onwards.
- Bladder ultrasound showed no significant decrease in bladder volume in the BUFC group by day 30.
Conclusions:
- Biomimetic urine flow control (BUFC) technology, integrated with urodynamic monitoring, demonstrates potential protective effects on bladder function.
- BUFC may mitigate the functional decline associated with long-term indwelling catheterization.
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