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Related Concept Videos

Vaccinations01:51

Vaccinations

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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
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Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
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Aging01:26

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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
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Active versus Passive Immunity01:31

Active versus Passive Immunity

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Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
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Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

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Same authorSame journal

Zeitschrift fur Gerontologie und Geriatrie·2026
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[STIKO Recommendation: MF59-Adjuvanted Influenza Vaccine for Individuals ≥ 60 Years of Age].

Deutsche medizinische Wochenschrift (1946)·2026
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MMW Fortschritte der Medizin·2026
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Real-world effectiveness and antibody responses of BNT162b2 vaccination in long-term care residents: A retrospective case-control study.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2026
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[Neuropsychological examinations at the Memory Clinic].

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Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
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[Vaccination in old age: an overview].

Anja Kwetkat1,2,3, Andreas Leischker4, Anne-Sophie Endres4,5

  • 1Medizinische Klinik IV, Klinik für Geriatrie und Palliativmedizin, Klinikum Osnabrück, Am Finkenhügel 1, 49076, Osnabrück, Deutschland. Anja.kwetkat@klinikum-os.de.

Zeitschrift Fur Gerontologie Und Geriatrie
|December 5, 2023
PubMed
Summary

Older adults receive updated vaccinations for herpes zoster, influenza, COVID-19, and pneumococcal disease. These specialized vaccines combat decreased immune response and comorbidities in individuals aged 60 and above.

Keywords:
COVID-19Herpes zosterImmune senescenceInfluenzaPneumococcus

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Area of Science:

  • Immunology
  • Public Health
  • Geriatrics

Context:

  • Aging populations exhibit increased susceptibility to infectious diseases.
  • Immune senescence and comorbidities can reduce vaccine efficacy in older adults.
  • Specific, more immunogenic vaccines are developed for the elderly population.

Purpose:

  • To outline the current standard vaccination recommendations for individuals aged 60 and above in Germany, as published by the Standing Commission on Vaccination (STIKO).
  • To highlight recent updates to the vaccination schedule, including herpes zoster, influenza, COVID-19, and pneumococcal vaccines.
  • To emphasize the importance of tailored vaccination strategies for older adults.

Summary:

  • Germany's STIKO recommends specific vaccines for individuals 60+ due to age-related immune decline.
  • Standard vaccinations now include adjuvanted inactivated herpes zoster vaccine (since 2018), high-dose quadrivalent influenza vaccine (since 2021), annual COVID-19 vaccination, and 20-valent pneumococcal conjugate vaccine.
  • These updates aim to enhance protection against common infectious diseases in this vulnerable demographic.

Impact:

  • Improved prevention of infectious diseases and associated complications in the elderly population.
  • Reduced healthcare burden through effective immunization strategies.
  • Enhanced public health through accessible and up-to-date vaccination information via the STIKO app.