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Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
Published on: February 22, 2019
[Vaccination in old age: an overview].
Anja Kwetkat1,2,3, Andreas Leischker4, Anne-Sophie Endres4,5
1Medizinische Klinik IV, Klinik für Geriatrie und Palliativmedizin, Klinikum Osnabrück, Am Finkenhügel 1, 49076, Osnabrück, Deutschland. Anja.kwetkat@klinikum-os.de.
Older adults receive updated vaccinations for herpes zoster, influenza, COVID-19, and pneumococcal disease. These specialized vaccines combat decreased immune response and comorbidities in individuals aged 60 and above.
Area of Science:
- Immunology
- Public Health
- Geriatrics
Context:
- Aging populations exhibit increased susceptibility to infectious diseases.
- Immune senescence and comorbidities can reduce vaccine efficacy in older adults.
- Specific, more immunogenic vaccines are developed for the elderly population.
Purpose:
- To outline the current standard vaccination recommendations for individuals aged 60 and above in Germany, as published by the Standing Commission on Vaccination (STIKO).
- To highlight recent updates to the vaccination schedule, including herpes zoster, influenza, COVID-19, and pneumococcal vaccines.
- To emphasize the importance of tailored vaccination strategies for older adults.
Summary:
- Germany's STIKO recommends specific vaccines for individuals 60+ due to age-related immune decline.
- Standard vaccinations now include adjuvanted inactivated herpes zoster vaccine (since 2018), high-dose quadrivalent influenza vaccine (since 2021), annual COVID-19 vaccination, and 20-valent pneumococcal conjugate vaccine.
- These updates aim to enhance protection against common infectious diseases in this vulnerable demographic.
Impact:
- Improved prevention of infectious diseases and associated complications in the elderly population.
- Reduced healthcare burden through effective immunization strategies.
- Enhanced public health through accessible and up-to-date vaccination information via the STIKO app.
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