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Updated: Jul 9, 2025
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Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
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Multiple Halo Nevi Induced by Intense Sun Exposure
Journal of Drugs in Dermatology : JDD
|December 5, 2023
Summary
Intense ultraviolet exposure may trigger the development of halo nevi, characterized by a white border around moles. This case highlights a potential environmental factor influencing these skin conditions.
Area of Science:
- Dermatology
- Environmental Medicine
Background:
- Halo nevi (Sutton's nevi) are benign melanocytic nevi surrounded by depigmentation.
- The etiology of halo nevi is not fully understood, with autoimmune and genetic factors often implicated.
Observation:
- A 38-year-old male presented with 26 new halo nevi on his trunk.
- The onset followed a 2-month period of significant sun and heat exposure in Alabama.
Findings:
- This case suggests a correlation between intense ultraviolet radiation exposure and the development of halo nevi.
- The patient's history indicates a potential environmental trigger for this dermatological phenomenon.
Implications:
- Ultraviolet exposure may be an underrecognized factor in halo nevus development.
- Further research is warranted to explore the role of environmental factors in the pathogenesis of halo nevi.
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