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A commentary on 'Preoperative renal insufficiency predicts postoperative adverse outcomes in a mixed surgical

Wei Guo1, Shu Li, Yuyu Zhao

  • 1Department of Nephrology, The Fourth People's Hospital of Shenyang, Shenyang, Liaoning, People's Republic of China.

International Journal of Surgery (London, England)
|December 5, 2023
PubMed
Abstract

No abstract available in PubMed .

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Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
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In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
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