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Updated: Jul 9, 2025

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
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Published on: April 29, 2010

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Processing of stalled replication forks in Bacillus subtilis

Begoña Carrasco1, Rubén Torres1, María Moreno-Del Álamo1

  • 1Department of Microbial Biotechnology, Centro Nacional de Biotecnología, CNB-CSIC, 3 Darwin Str, 28049 Madrid, Spain.

FEMS Microbiology Reviews
|December 5, 2023
PubMed
Summary

Bacillus subtilis uses various proteins to overcome replication stress and maintain genomic stability. These proteins help restart DNA synthesis after replication fork arrest, preventing genomic instability.

Keywords:
DNA damage toleranceRNA polymerase hubRecA hubSsbA hubfork reversalreplisome disassemblytemplate switching

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