Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

429
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
429

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-Term Real-Time Tracking of Morphology and Migration of Neuronal Cells under Oxidative Stress.

Chemical & biomedical imaging·2025
Same author

Label-Free Mapping of Multivalent Binding Pathways with Ligand-Receptor-Anchored Nanopores.

Journal of the American Chemical Society·2024
Same author

HFM-Tracker: a cell tracking algorithm based on hybrid feature matching.

The Analyst·2024
Same author

Electrochemical Visualization of Single-Molecule Thiol Substitution with Nanopore Measurement.

ACS measurement science au·2024
Same author

One-Component Dual-Readout Aggregation-Induced Emission Nanobeads for Qualitative and Quantitative Detection of C-Reactive Protein at the Point of Care.

Analytical chemistry·2023
Same author

Observing Confined Local Oxygen-induced Reversible Thiol/Disulfide Cycle with a Protein Nanopore.

Angewandte Chemie (International ed. in English)·2023
Same journal

Comparative performance of biopolymer-supported graphitic carbon nitride nanosheets for electrochemical carcinoembryonic antigen cancer biomarker detection in serum samples using smartphone device.

Mikrochimica acta·2026
Same journal

A non-enzymatic sensor based on rGO/Pt NPs/Fc-Tyr/POPD nanocomposite for hydrogen peroxide determination in liver cancer tissues.

Mikrochimica acta·2026
Same journal

MnO<sub>2</sub>/Au-Ag nanozyme-GOx cascade system for sensitive colorimetric glucose detection and test strip applications.

Mikrochimica acta·2026
Same journal

Recent advances and progress in tungsten trioxide and its hybrid materials based sensors for environmental monitoring and healthcare systems: analytical performance, challenges and future trends.

Mikrochimica acta·2026
Same journal

Hollow nanozyme with improved peroxidase-like activity for nitrite detection.

Mikrochimica acta·2026
Same journal

Photo-responsive Ce-hemin nanozyme-based portable colorimetric sensor for tetracyclines assay.

Mikrochimica acta·2026
See all related articles

Related Experiment Video

Updated: Jul 9, 2025

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs
03:33

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs

Published on: November 17, 2023

2.3K

Paper-based substrates for surface-enhanced Raman spectroscopy sensing.

Yue Cao1, Yang Sun2, Ru-Jia Yu3,4

  • 1Department of Forensic Medicine, Nanjing Medical University, Nanjing, 211166, People's Republic of China. ycao@njmu.edu.cn.

Mikrochimica Acta
|December 5, 2023
PubMed
Summary
This summary is machine-generated.

Flexible paper-based substrates enhance surface-enhanced Raman scattering (SERS) analysis. This review covers fabrication methods, applications in detecting various substances, and future prospects for these versatile SERS platforms.

Keywords:
Biological sensingClinical diagnosisFlexible substratePaper-based substrateSurface-enhanced Raman scattering (SERS)

More Related Videos

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

20.4K
A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants
08:13

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants

Published on: February 19, 2016

9.4K

Related Experiment Videos

Last Updated: Jul 9, 2025

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs
03:33

Author Spotlight: Development and Application of SERS Flexible Substrates Using Synthesized AgNPs

Published on: November 17, 2023

2.3K
Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

20.4K
A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants
08:13

A Filter-based Surface Enhanced Raman Spectroscopic Assay for Rapid Detection of Chemical Contaminants

Published on: February 19, 2016

9.4K

Area of Science:

  • Analytical Chemistry
  • Materials Science

Background:

  • Surface-enhanced Raman scattering (SERS) is a highly sensitive analytical technique utilizing plasmonic surfaces.
  • Flexible SERS substrates, especially paper-based ones, offer user-friendly sample interaction.
  • Advancements in substrate fabrication are crucial for expanding SERS applications.

Purpose of the Study:

  • To review recent progress in flexible SERS substrates, focusing on paper-based materials.
  • To summarize preparation methods and advantages of paper-based SERS substrates.
  • To discuss the applications and future potential of these substrates in various detection scenarios.

Main Methods:

  • Review of literature on flexible and paper-based SERS substrate fabrication.
  • Analysis of reported applications in abiotic and biological sample detection.
  • Discussion of challenges and future directions for paper-based SERS technology.

Main Results:

  • Various fabrication techniques for paper-based SERS substrates have been developed.
  • Paper-based SERS substrates show significant potential in detecting analytes in diverse matrices.
  • Clinical diagnosis is a promising application area for these flexible SERS platforms.

Conclusions:

  • Paper-based SERS substrates represent a significant advancement in sensitive, portable analytical tools.
  • Further research into fabrication and application will broaden the utility of these substrates.
  • Addressing current challenges is key to realizing the full potential of paper-based SERS in clinical and other fields.