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Related Concept Videos

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
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Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
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Inflammatory Bowel Disease IV: Pharmacological Management01:29

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Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
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Hypersensitivities01:30

Hypersensitivities

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Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
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Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2...
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Related Experiment Video

Updated: Jul 9, 2025

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
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Treatments for atopic dermatitis.

Gayle Ross1

  • 1Royal Melbourne Hospital, East Malvern Dermatology, Melbourne.

Australian Prescriber
|December 6, 2023
PubMed
Summary

Atopic dermatitis management includes non-drug and drug therapies for skin clearance. Identifying and avoiding triggers, alongside consistent moisturizing, are key for managing this common skin condition.

Area of Science:

  • Dermatology
  • Immunology
  • Allergy

Background:

  • Atopic dermatitis (AD) is a chronic inflammatory skin condition, often starting in childhood but also affecting adults.
  • While allergies are common, not all AD patients have them; trigger avoidance is crucial for many.
  • Effective management aims for skin clearance and symptom relief.

Purpose of the Study:

  • To outline current management strategies for atopic dermatitis.
  • To detail various treatment options, from basic skincare to advanced systemic therapies.
  • To emphasize the importance of personalized treatment based on disease severity and affected areas.

Main Methods:

  • Review of established and emerging treatments for atopic dermatitis.
  • Discussion of non-pharmacological interventions including skincare and trigger avoidance.
Keywords:
Janus kinase inhibitorsatopic dermatitiscalcineurin inhibitorscorticosteroidsimmunosuppressionphototherapy

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  • Overview of pharmacological treatments: topical corticosteroids, calcineurin inhibitors, antihistamines, phototherapy, and systemic agents.

    • Main Results:

    • Basic skincare (soap substitutes, bath oils, moisturizers) is fundamental for all patients.
    • Topical corticosteroids are the primary drug treatment, with selection depending on the affected site.
    • Advanced therapies like bleach baths, wet dressings, phototherapy, and systemic agents (immunosuppressants, dupilumab, upadacitinib) are available for severe or refractory cases.

    Conclusions:

    • Comprehensive management of atopic dermatitis involves a multi-faceted approach.
    • Tailoring treatments to individual patient needs, including trigger identification and appropriate medication choice, is essential.
    • Newer systemic therapies offer improved options for severe and chronic atopic dermatitis.