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Updated: Jul 9, 2025

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
Testicular involvement in mantle cell lymphoma: An analysis of 16 patients
Samer Alkhalili1, Dharmini Manogna2, Hana Safah2
1Deming Department of Medicine, Tulane University School of Medicine, 1430 Tulane Ave, New Orleans, LA 70112, United States.
Abstract:
Mantle cell lymphoma (MCL) with testicular involvement is a rare presentation and only a few cases have been described in the literature. We present a case of MCL with testicular involvement and the first analysis of all previously reported cases assessing trends in immunohistochemical features, prognostic indicators, and survival. Our data suggest that among all MCL, testicular MCL is more likely to present with aggressive features: blastoid/pleomorphic morphology, high Ki-67 proliferative index, and CNS involvement. Testicular MCL is also associated with shorter overall survival.
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