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Schwannoma and Post-vaccine Changes: A Case Report
Martha-Lilia Tena-Suck1, Steven-Andrés Piña-Ballantyne2, Jesús Cienfuegos-Meza2
1Neuropathology, Instituto Nacional de Neurología y Neurocirugia Manuel Velasco Suárez, Mexico, MEX.
Cureus
|December 6, 2023
Summary
This case study discusses a cervical schwannoma in a patient who developed COVID-19 and later received a Moderna vaccine. Post-surgery, extensive tumor necrosis was observed, possibly linked to the vaccine.
Area of Science:
- Neurology
- Oncology
- Immunology
Background:
- Schwannomas are typically benign nerve sheath tumors.
- Necrosis and hemorrhage are uncommon in schwannomas.
- Cervical schwannomas can cause neurological symptoms like paresthesia.
Observation:
- A 28-year-old male presented with a C2-C4 cervical schwannoma and COVID-19 symptoms.
- The patient underwent successful tumor resection one year after diagnosis.
- Extensive tumor necrosis with foamy macrophages was noted post-surgery.
Findings:
- Histological examination confirmed schwannoma resection.
- The observed necrosis suggests a potential association with recent vaccination.
- The patient received the Moderna vaccine one week prior to surgery.
Implications:
- This case highlights a rare presentation of a cervical schwannoma.
- Investigating potential links between COVID-19 vaccination and tumor changes is warranted.
- Further research is needed to understand vaccine-induced immunomodulation in benign tumors.
