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AAPM Task Group Report 311: Guidance for performance evaluation of fluorescence-guided surgery systems.

Brian W Pogue1,2, Timothy C Zhu3, Vasilis Ntziachristos4

  • 1Department of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin, USA.

Medical Physics
|December 6, 2023
PubMed
Summary

This study addresses the growing need for standardized quality assessment in fluorescence-guided surgery (FGS) systems. It proposes objective test methods and guidelines for consistent performance evaluation across diverse FGS devices.

Keywords:
fluorescencefluorophoreindocyanine greeinterventionopticalsurgery

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Area of Science:

  • Medical Imaging
  • Surgical Technology
  • Biomedical Engineering

Background:

  • Fluorescence-guided surgery (FGS) imaging and interventions have significantly expanded over the past decade.
  • Increasing clinical adoption of FGS has led to a proliferation of diverse systems with varying designs and performance requirements.
  • The heterogeneity of FGS systems complicates the establishment of uniform performance goals and quality assessment.

Purpose of the Study:

  • To establish common knowledge bases and a quality assessment paradigm for fluorescence-guided surgery (FGS) devices.
  • To identify key image quality characteristics and objective test methods for consistent FGS system evaluation.
  • To develop professional guidelines for the effective translation and utilization of FGS technology.

Main Methods:

  • Identification of fundamental image quality characteristics relevant to FGS systems.
  • Development of objective test methods using tissue-simulating phantoms.
  • Establishment of suggested guidelines, personnel needs, and professional knowledge bases.

Main Results:

  • Proposed a framework for determining key image quality characteristics for FGS devices.
  • Outlined objective test methods and tissue-simulating phantoms for performance assessment.
  • Suggested guidelines for personnel and knowledge bases to ensure consistent FGS quality.

Conclusions:

  • Standardized objective test methods and guidelines are feasible and necessary for diverse FGS systems.
  • Establishing consistent conventions across FGS devices will facilitate effective translation and clinical use.
  • This work provides a foundation for quality assessment and professional development in fluorescence-guided surgery.