Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Seven-Year Valve Durability With Transcatheter or Surgical Aortic Valve Replacement: An Ad Hoc Analysis of the PARTNER 3 Randomized Clinical Trial.

JAMA cardiology·2026
Same author

Restoration of 3-dimensional aortic hemodynamics after the Ross procedure for unicuspid aortic valve disease using 4-dimensional flow magnetic resonance imaging.

JTCVS structural and endovascular·2026
Same author

Left and Right Heart Remodelling at 1 Year After Transcatheter Versus Surgical Aortic Valve Replacement: A Speckle-Tracking Echocardiography Study.

Interdisciplinary cardiovascular and thoracic surgery·2026
Same author

Preoperative Lung Function Assessment and the Impact of Spirometry Misdiagnosis on Mortality Following Cardiac Surgery.

Journal of cardiothoracic and vascular anesthesia·2026
Same author

The impact of leaflet resection versus leaflet preservation on left ventricular reverse remodelling after mitral valve repair: insights from the UK mini mitral trial.

Journal of cardiothoracic surgery·2026
Same author

Pathogen-specific immune responses might underlie divergent outcomes of coronavirus and influenza infection in the natural porcine host.

Communications biology·2026

Related Experiment Video

Updated: Jul 9, 2025

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

11.7K

Limited versus full sternotomy for aortic valve replacement.

Bilal H Kirmani1,2,3, Sion G Jones4, Andrew Muir1

  • 1Cardiothoracic Surgery, Liverpool Heart and Chest Hospital, Liverpool, UK.

The Cochrane Database of Systematic Reviews
|December 6, 2023
PubMed
Summary
This summary is machine-generated.

Minimally invasive aortic valve replacement via limited sternotomy shows similar mortality to conventional median sternotomy but may increase procedure times. Postoperative blood loss is likely lower, though evidence quality varies.

More Related Videos

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.4K
Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.1K

Related Experiment Videos

Last Updated: Jul 9, 2025

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

11.7K
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.4K
Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.1K

Area of Science:

  • Cardiovascular Surgery
  • Minimally Invasive Procedures
  • Aortic Valve Disease Management

Background:

  • Aortic valve disease is commonly treated with cardiac surgery, traditionally via median sternotomy.
  • Minimally invasive approaches using limited sternotomy are emerging, raising questions about safety and efficacy.
  • This review updates previous findings on limited sternotomy versus median sternotomy for aortic valve replacement.

Approach:

  • Systematic review and meta-analysis of randomized controlled trials (RCTs) comparing limited upper hemi-sternotomy to full median sternotomy.
  • Searches conducted across major databases (CENTRAL, MEDLINE, Embase) up to August 2021.
  • Included 14 RCTs with 1395 participants, assessing various patient-relevant outcomes.

Key Points:

  • Limited sternotomy may have little to no effect on mortality (low-certainty evidence).
  • Procedure times (cardiopulmonary bypass and aortic cross-clamp) may slightly increase, with very uncertain evidence.
  • Postoperative blood loss appears probably lower with limited sternotomy (moderate-certainty evidence).
  • Pain scores and quality of life show little to no difference (low-certainty evidence).
  • Limited sternotomy may be more costly at index admission in the UK NHS (low-certainty evidence).

Conclusions:

  • Evidence certainty ranges from very low to moderate, with limitations in sample size and potential bias.
  • Widespread adoption of minimally invasive limited sternotomy requires further high-quality, adequately powered RCTs.
  • Future research should include robust cost analyses and detailed quality of life assessments.