Management of post-mortem examination in SARS-CoV-19 infections

Mattia Riefolo1,2, Francesca Ambrosi2,3, Alessandra De Palma4

  • 1Pathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

Pathologica
|December 6, 2023
PubMed

Insights

Guidelines for managing autopsies during the SARS-CoV-19 pandemic are presented, covering Italian legal requirements, autopsy room specifications, and histological sampling techniques for accurate examination.

Area of Science:

  • Forensic Pathology
  • Infectious Disease Management

Background:

  • The SARS-CoV-19 pandemic necessitated specific protocols for post-mortem examinations.
  • Standard autopsy procedures required adaptation to mitigate transmission risks.

Purpose of the Study:

  • To provide an overview of autopsy management during the SARS-CoV-19 epidemic.
  • To address legal, logistical, and technical aspects of conducting autopsies in the context of COVID-19.

Main Methods:

  • Review of Italian legislation pertaining to autopsies during public health emergencies.
  • Description of essential characteristics for autopsy suites handling infectious cases.
  • Recommendations for tissue sampling for histological analysis.

Main Results:

  • Outlined legal framework for SARS-CoV-19 related autopsies in Italy.
  • Detailed requirements for autopsy room safety and infrastructure.
  • Specified histological sampling strategies for effective disease characterization.

Conclusions:

  • Adherence to specific legal and safety guidelines is crucial for SARS-CoV-19 autopsies.
  • Appropriate histological sampling ensures comprehensive post-mortem analysis.
  • Standardized protocols enhance the safety and efficacy of forensic investigations during pandemics.

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