Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA Topoisomerases02:02

DNA Topoisomerases

31.4K
Topoisomerases are enzymes that relax overwound DNA molecules during various cell processes, including DNA replication and transcription. These enzymes regulate positive and negative DNA supercoiling without changing the nucleotide sequence. DNA overwinding in a clockwise direction results in positively supercoiled DNA, whereas underwinding in a counterclockwise direction produces negatively supercoiled DNA.
Types and Mechanism of action
Topoisomerases are divided into two main types. ...
31.4K
The DNA Helix01:07

The DNA Helix

20.8K
Deoxyribonucleic acid, or DNA, is the genetic material responsible for passing traits from generation to generation in all organisms and most viruses. DNA is composed of two strands of nucleotides that wind around each other to form a spring-like structure called a double helix. However, the double helix is not perfectly symmetrical. Instead, there are regularly occurring grooves in the structure. The major groove occurs where the sugar-phosphate backbones are relatively far apart. This space...
20.8K
Karyotyping01:17

Karyotyping

61.2K
Overview
61.2K
Circuit Terminology01:14

Circuit Terminology

1.6K
An electrical network is a system composed of interconnected elements, such as resistors, capacitors, inductors, and voltage or current sources. Unlike a circuit, an electrical network does not necessarily form a closed path. In other words, while all circuits can be considered networks due to their interconnected nature, not every network qualifies as a circuit.
A circuit, on the other hand, is also an interconnected system of electrical elements but must contain one or more closed paths.
1.6K
Chromosome Structure02:40

Chromosome Structure

22.8K
A functional eukaryotic chromosome must contain three elements: a centromere, telomeres, and numerous origins of replication.
The centromere is a DNA sequence that links sister chromatids. This is also where kinetochores, protein complexes to which spindle microtubules attach, are constructed after the chromosome is replicated. The kinetochores allow the spindle microtubules to move the chromosomes within the cell during cell division.
Telomeres consist of non-coding repetitive nucleotide...
22.8K
DNA as a Genetic Template02:05

DNA as a Genetic Template

21.9K
Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...
21.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<i>Capsicum annuum</i> RPW8 Confers Broad-Spectrum Resistance against Multiple Pathogens.

Journal of agricultural and food chemistry·2026
Same author

CaNAC61, CaNAC79, and CaNAC92 Act as Negative Regulators in Pepper Defense Response Against <i>Phytophthora capsici</i>.

Biology·2026
Same author

The influence of job content and autonomy on psychological well-being through work identity and job crafting among pharmacists in Pakistan.

PloS one·2026
Same author

Retraction Note: Mathematical modeling and computation of NM-polynomial indices for physicochemical properties prediction.

Scientific reports·2026
Same author

Assessment of centesimal composition, minerals, amino acids and antioxidant activity of ten cultivars of sweet potato for promoting industrial application as steamed slices.

Journal of food science and technology·2026
Same author

Chitosan-quercetin complex containing nanospheres for targeted delivery of methotrexate against MCF-7 breast cancer cells.

International journal of biological macromolecules·2026

Related Experiment Video

Updated: Jul 9, 2025

Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C
09:32

Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C

Published on: October 14, 2022

3.5K

Connection number topological aspect for backbone DNA networks.

Ali Ahmad1, Ali N A Koam2, Ibtisam Masmali2

  • 1Department of Information Technology and Security, College of Computer Science and Information Technology, Jazan University, Jazan, Saudi Arabia.

The European Physical Journal. E, Soft Matter
|December 6, 2023
PubMed
Summary

This study introduces the Connection Number (CN) to analyze DNA network topology and information flow. Researchers computed various connection-based indices for DNA networks, revealing insights into their structural properties.

Keywords:
05C0792E10

More Related Videos

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers
08:00

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

6.9K
In-Nucleus Hi-C in Drosophila Cells
11:58

In-Nucleus Hi-C in Drosophila Cells

Published on: September 15, 2021

4.2K

Related Experiment Videos

Last Updated: Jul 9, 2025

Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C
09:32

Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C

Published on: October 14, 2022

3.5K
DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers
08:00

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

6.9K
In-Nucleus Hi-C in Drosophila Cells
11:58

In-Nucleus Hi-C in Drosophila Cells

Published on: September 15, 2021

4.2K

Area of Science:

  • Chemical graph theory
  • Computational biology
  • Network science

Background:

  • DNA networks exhibit complex topological characteristics crucial for biological function.
  • Understanding network structure aids in analyzing information flow and robustness.
  • The Connection Number (CN) is an emerging metric for network analysis.

Purpose of the Study:

  • To investigate the topological properties of DNA networks using the Connection Number (CN).
  • To compute novel connection-based topological descriptors for DNA networks.
  • To elucidate the role of CN in characterizing DNA network structure and dynamics.

Main Methods:

  • Utilized rigorous mathematical modeling and analysis.
  • Employed direct computation methods for topological descriptors.
  • Calculated hyper Zagreb connection index, augmented connection index, and others.

Main Results:

  • Established the significance of the Connection Number in DNA network analysis.
  • Computed several connection-based topological indices for backbone DNA and its barycentric subdivision networks.
  • Demonstrated the utility of these descriptors in understanding network robustness.

Conclusions:

  • The Connection Number provides profound insights into DNA network topology and dynamics.
  • Connection-based topological descriptors are valuable tools for studying complex biological networks.
  • This research contributes to the understanding of DNA network structures through chemical graph theory.