Related Experiment Video
Updated: Jul 9, 2025

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
Failure to rescue following postoperative pneumonia in pediatrics: Is there a racial disparity?
Jalen Warren1, Anna Gibbs2, Christian Mpody3
1Ohio University Heritage College of Osteopathic Medicine, Dublin Campus and Ohio University, Athens, Ohio, USA.
Insights
This study found no racial disparities in failure to rescue (mortality) following postoperative pneumonia in children. Further research is needed to address racial gaps in postoperative mortality.
Area of Science:
- Pediatric Surgery
- Healthcare Disparities
- Patient Safety
Background:
- Racial disparities in healthcare are well-documented, but less is known about disparities in failure to rescue after major adverse events.
- Failure to rescue, defined as mortality following a major adverse event, is a critical measure of hospital quality.
- Postoperative pneumonia is a serious complication that can lead to failure to rescue.
Purpose of the Study:
- To examine the association between race and failure to rescue following postoperative pneumonia in children.
- To determine if Black children experience higher rates of mortality after developing pneumonia post-surgery compared to White children.
Main Methods:
- Utilized the National Surgical Quality Improvement Program-Pediatrics Participant Use Data File (2012-2022).
- Included Black and White children under 18 who developed pneumonia after inpatient surgery.
- Used logistic regression to compare failure to rescue (mortality) rates between racial groups, adjusting for multiple covariates.
Main Results:
- The study included 3139 children (25.7% Black, 74.3% White) who developed postoperative pneumonia.
- Overall failure to rescue occurred in 3.7% of children (3.5% White, 4.3% Black).
- After adjustment, the odds of failure to rescue for Black children did not differ significantly from White children (aOR: 1.00; 95% CI: 0.62-1.61).
Conclusions:
- No significant racial disparities were found in failure to rescue following postoperative pneumonia in children.
- Future research should investigate race and failure to rescue in other postoperative complications to reduce racial gaps in mortality.
Introduction:
Racial disparities in measures of health and healthcare processes are well described. Limited work exists on disparities in failure to rescue - hospital mortality following a major adverse event. Postoperative pneumonia is a serious, potentially preventable adverse event that often leads to death, i.e., failure to rescue. This study examined the association of racial grouping with failure to rescue following postoperative pneumonia.
Methods:
We utilized the National Surgical Quality Improvement Program-Pediatrics Participant Use Data File to assemble a cohort of children <18 years who underwent inpatient surgery from 2012 to 2022. We included Black and White patients who developed pneumonia following an index surgery. The primary outcome was failure to rescue, defined as mortality following postoperative pneumonia. We used logistic regression models to estimate the odds ratio and 95% confidence intervals of failure to rescue, comparing Black and White children.
Results:
The study cohort included 3139 children <18 years who developed pneumonia following inpatient surgery. Of those, 2333 (74.3%) were White and 806 (25.7%) were Black. Failure to rescue occurred in 117 of the children (3.7%); 82 were White (3.5%) and 35 were Black (4.3%). After adjusting for gender, age, American Society of Anesthesiologists Physical Status classification, emergent/urgent vs. elective case status, year of operation, and pre-existing comorbidities, the odds of failure to rescue for Black children with postoperative pneumonia did not differ from White children (adjusted-Odds Ratio: 1.00; 95% Confidence Interval 0.62-1.61; p-value = .992).
Conclusion:
We found no significant difference in the odds of failure to rescue following postoperative pneumonia between Black or White children. To improve postoperative care for all children and to narrow the racial gap in postoperative mortality, future studies should continue to investigate the association of race with failure to rescue following other postoperative complications.
Related Concept Videos
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Pneumonia III: Complications and Assessment
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
Acute Respiratory Failure-I
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...

