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Related Concept Videos

Equipments Used to Measure Body Temperature01:13

Equipments Used to Measure Body Temperature

Body temperature can be assessed using various devices and measured in Celsius or Fahrenheit.
Glass-bulb Thermometer:
Glass-bulb thermometers are hollow glass tubes with a bulb tip containing liquid such as ethanol or mercury. Historically, glass bulb mercury thermometers were the standard device to measure body temperature. Today, mercury thermometers are prohibited in many countries due to the hazardous effects of mercury and the risk of exposure if the glass bulb breaks. In general,...

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Thermal Measurement Techniques in Analytical Microfluidic Devices
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Quantitative Microscale Thermometry in Droplets Loaded with Gold Nanoparticles.

Lucas Sixdenier1, Guillaume Baffou2, Christophe Tribet1

  • 1PASTEUR, Département de chimie, École normale supérieure, PSL University, Sorbonne Université, CNRS, 75005 Paris, France.

The Journal of Physical Chemistry Letters
|December 6, 2023
PubMed
Summary
This summary is machine-generated.

Measuring microscale temperature gradients from gold nanoparticles (AuNPs) is difficult. This study presents a label-free method using microscopy and simulations to accurately determine temperature in 3D AuNP systems without calibration.

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Area of Science:

  • Nanotechnology
  • Plasmonics
  • Biomedical Engineering

Background:

  • Gold nanoparticles (AuNPs) exhibit thermoplasmonic properties, converting light to heat.
  • Accurate measurement of microscale temperature gradients from 3D AuNP assemblies is challenging.
  • Existing methods often require extrinsic calibration or are unsuitable for complex 3D distributions.

Purpose of the Study:

  • To develop a novel, label-free thermometry approach for quantifying heat dissipation from 3D AuNP systems.
  • To enable non-invasive temperature measurements in microscale environments.
  • To validate the method using a model system of AuNP-loaded emulsion microdroplets.

Main Methods:

  • Combining quantitative wavefront microscopy with numerical simulations.
  • Utilizing a 3D model system of emulsion microdroplets containing AuNPs.
  • Inferring heating power dissipated by AuNPs under laser irradiation.

Main Results:

  • Successfully inferred the heating power dissipated by AuNPs within the 3D model system.
  • Determined the temperature reached in microdroplets under laser irradiation.
  • Demonstrated a label-free approach without the need for extrinsic calibration.

Conclusions:

  • The developed thermometry method provides accurate, non-invasive temperature measurements in 3D microsystems.
  • This versatile technique is promising for applications involving AuNPs as colloidal heat sources, such as photothermal drug delivery.
  • The approach overcomes limitations of previous methods for measuring microscale temperature gradients.