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Published on: May 5, 2022
BULLOUS VARIANT OF CENTRAL SEROUS CHORIORETINOPATHY IN GOODPASTURE DISEASE: A CASE REPORT AND REVIEW OF LITERATURE
Jonathan C Tsui1,2, Robert M Carroll1,3, Alexander J Brucker1
1Department of Ophthalmology, Perelman School of Medicine, Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania.
Purpose:
The aim of this study was to describe a case of bullous variant of central serous chorioretinopathy (CSR) in Goodpasture disease (GD) compared with an identical twin without GD and summarize the literature on ocular manifestations of GD.
Methods:
This was an interventional/observational case report and literature review.
Results:
A 46-year-old White woman with a history of GD presented with decreased vision. She demonstrated bilateral multifocal pigment epithelial detachments and a large inferior exudative retinal detachment in the left eye consistent with bilateral CSR with bullous variant CSR in the left eye. Despite treatment, her disease remained refractory, with final VA of 20/200 in the left eye. The patient's identical twin sister did not have GD and demonstrated milder CSR on presentation with a more typical, self-limited disease course. Her final VA was 20/20 bilaterally.
Conclusion:
Goodpasture disease is associated with severe manifestations of CSR (exudative retinal detachment). Additional studies focusing on the association between GD and CSR severity may be of interest.
