Related Experiment Video
Updated: Jul 9, 2025

Enhancing Efficiency and Radiolabeling Yields of Carbon-11 Radioligands for Clinical Research Using the Loop Method
Published on: December 20, 2024
Production of pharmaceutical grade [201Tl]Thallous chloride using 30 MeV cyclotron
Sankha Chattopadhyay1, Luna Barua1, D G Mahesh1
1Medical Cyclotron Facility, Regional Centre, Board of Radiation and Isotope Technology, Kolkata, India.
Abstract:
Multiple patient doses of [201Tl]TlCl has been produced using electrodeposited enriched 203Tl in 30 MeV cyclotron (Cyclone-30) with 28 MeV proton energy at 50 μA beam current for 8 h. Ion Exchange Column Chromatography (IECC) and liquid-liquid extraction has been employed for semi-automated radiochemical separation and purification of produced [201Tl]TlCl. The produced [201Tl]TlCl was used in coronary artery disease (CAD) patients.

