Optimal resistance exercise training parameters for stroke recovery: A protocol for a systematic review

Area of Science:

• Neurology
• Rehabilitation Medicine
• Exercise Science

Background:

• Stroke affects millions annually, often impairing muscle strength and physical function, critical for recovery.
• Resistance exercise training (RT) shows promise for improving strength post-stroke.
• Current RT prescriptions may not be optimized for comprehensive stroke recovery, necessitating evaluation of specific parameters.

Purpose of the Study:

• To determine the effects of resistance exercise training (RT) on stroke recovery.
• To examine how RT parameters (frequency, intensity, type, duration) influence intervention effectiveness.

Main Methods:

• Systematic review of randomized controlled trials (RCTs) comparing RT to no exercise or usual care in adults with stroke.
• Comprehensive literature search across eight databases and two clinical trials registries.
• Meta-analyses and meta-regression will be used to synthesize data and explore parameter influences.

Main Results:

• Expected to synthesize evidence on RT's impact on physical function, strength, cognition, and quality of life post-stroke.
• Meta-regression will identify relationships between RT parameters and recovery outcomes.
• Results will highlight effective RT strategies for stroke rehabilitation.

Conclusions:

• This review will provide evidence-based recommendations for optimizing RT prescription in stroke recovery.
• Findings will guide clinicians and researchers in designing more effective RT interventions for stroke survivors.
• The study aims to enhance functional outcomes and quality of life for individuals post-stroke.