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Updated: Jul 9, 2025

Culturing of Human Nasal Epithelial Cells at the Air Liquid Interface
Published on: October 8, 2013
Impact of Atmospheric Conditions on Epistaxis Incidence
Alkmini Gatsounia1, Georgios Schinas2, Gerasimos Danielides3
1Otolaryngology-Head and Neck Surgery, University General Hospital of Patras, Patras, GRC.
Purpose:
A possible correlation between epistaxis occurrence and atmospheric parameters' variation has long been hypothesized. This study aims to determine whether cumulative epistaxis incidence is related to seasonal variation and its relationship to monthly, weekly, and daily recordings of atmospheric measurements in the city of Patras, Greece.
Methods:
In this retrospective study, data concerning the patients who presented with active epistaxis at the ED of a tertiary university hospital in Western Greece between January 2020 and December 2021 were collected. Only cases of spontaneous epistaxis were included in the study; patients bleeding secondarily due to a known mechanical cause, i.e., a tumor, trauma, or surgery, were excluded. The measurements of atmospheric parameters were supplied by the Department of Physics, University of Patras.
Results:
In total, 230 cases of spontaneous, active epistaxis were evaluated in the ED over the course of the study. The median frequency of epistaxis presentations was two cases per week. Most of the patients were male, comprising 62.6% of the cohort, and the median age stood at 70 years, with an interquartile range (IQR) of 54 to 81 years. A minor yet statistically significant negative correlation between the incidence of epistaxis and mean relative humidity was observed both on a daily and weekly basis. Mean relative humidity emerged as a significant predictor for the incidence of epistaxis, both daily and weekly. Significantly lower mean relative humidity values were recorded during weeks with a high incidence of epistaxis cases (57.72% vs. 63.39%, p = 0.02). No discernible seasonality was observed in the frequency of epistaxis presentations to the ED.
Conclusion:
A modest yet statistically significant trend toward fewer epistaxis cases was observed in conditions of higher ambient humidity during the study period in the region of Western Greece.
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