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SARS-CoV-2 seroprevalence and respiratory disease disability claims in Mexico City Metropolitan Area
David Barros-Sierra1, Rodrigo Zepeda-Tello2, Marcela Tamayo-Ortiz3
1Dirección de Prestaciones Económicas y Sociales, Instituto Mexicano del Seguro Social. Ciudad de México, Mexico.. dr.davidbarros@gmail.com.
Objective:
To characterize the impact of SARS-CoV-2 infection in workers from an essential large-scale company in the Greater Mexico City Metropolitan Area using point prevalence of acute infection, point prevalence of past infection through serum antibodies and respiratory disease short-term disability claims (RD-STDC).
Materials And Methods:
Four randomized surveys, three during 2020 before and one after (December 2021) vaccines' availability.
Outcomes:
point prevalence of acute infection through saliva PCR (polymerase chain reaction) testing, point prevalence of past infection through serum antibodies against Covid-19, RD-STDC and prevalence of symptoms during the previous six months.
Results:
Prevalence of SARS-CoV-2 cases was 1.29-4.88%, on average, a quarter of participants pre-vaccination were seropositive; over half of participants with a RD-STDC had antibodies. The odds of having antibodies were 6-7 times more among workers with an RD-STDC.
Conclusions:
High antibody levels against Covid-19 in this study population reflects that coverage is high among workers in this industry. STDCs are a useful tool to track workplace epidemics.
