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Updated: Jul 9, 2025

Conventional BODIPY Conjugates for Live-Cell Super-Resolution Microscopy and Single-Molecule Tracking
Published on: June 8, 2020
Synthesis, structure, photophysical property, stability of tetraphenylethylene-based boranil, and applications in
Yang Liu1, Shimin Zhou1, Zhiqiang Liu1
1State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, China; Shenzhen Research Institute of Shandong University, Shenzhen 518057, China.
Abstract:
A new family of tetraphenylethylene-based N,O-chelated boranil complexes (TPE-BAs) with aggregation-induced emission (AIE) characteristics were developed. X-ray crystallographic analysis indicated that the terminal substituents on the aniline moiety significantly affected the intermolecular stacking mode, thereby influencing the photophysical properties. The stabilities of these compounds are closely related to the substituents on the aniline moiety. Electron-donor-substituted TPE-BA-OMe exhibited the best stability, whereas the electron-acceptor-substituted compounds exhibited poor stability. Benefitting from its AIE properties and suitable lipophilicity, TPE-BA-OMe served as an excellent fluorescent probe for the specific bioimaging of lipid droplets in living cells.
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