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Colloid shift following blunt trauma.

R C Briggs, S M Amberson

    Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
    |February 1, 1987
    PubMed
    Summary
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    Blunt trauma can cause a reversed liver-spleen activity ratio (colloid shift) in spleen imaging. This unexpected finding, possibly due to reticuloendothelial system stimulation, can persist long after injury.

    Area of Science:

    • Nuclear medicine
    • Radiology
    • Trauma imaging

    Background:

    • Spleen imaging with technetium-99m sulfur colloid is a diagnostic tool.
    • Colloid shift, an altered liver-spleen activity ratio, is typically associated with specific predisposing factors.

    Purpose of the Study:

    • To evaluate the incidence and characteristics of colloid shift in patients with blunt chest or upper abdominal trauma.
    • To investigate potential causes for unexpected colloid shift findings.

    Main Methods:

    • Retrospective analysis of 33 patients undergoing spleen imaging post-blunt trauma.
    • Assessment of liver-spleen activity ratios on [99mTc]sulfur colloid scans.

    Main Results:

    • Nineteen out of 33 patients (57.6%) exhibited colloid shift.

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  • Colloid shift was observed as early as 2 hours and persisted up to 188 days post-trauma.
  • No predisposing factors for colloid shift were identified in the study cohort.

    • Conclusions:

    • Colloid shift is a notable finding in spleen imaging following blunt chest/abdominal trauma.
    • The mechanism is hypothesized to involve reticuloendothelial system stimulation.
    • This finding has implications for interpreting spleen scans in trauma patients.