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Development of a standalone delivery sequence model for proton arc therapy
Gang Liu1,2,3, Lewei Zhao4, Peilin Liu5
1Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Medical Physics
|December 8, 2023
Summary
Spot-scanning proton arc (SPArc) therapy significantly improves treatment efficiency, reducing delivery time by 58.1% and increasing daily throughput by 30%. This study introduces the first SPArc delivery sequence model for simulating and assessing efficiency gains in proton therapy.
Area of Science:
- Medical Physics
- Radiation Oncology
- Cancer Treatment Technology
Background:
- Spot-scanning proton arc (SPArc) therapy enables continuous proton irradiation during gantry rotation.
- Previous research demonstrated SPArc plan delivery on the IBA ProteusONE DynamicARC prototype.
Purpose of the Study:
- To develop the first Spot-scanning proton arc delivery sequence model (DSMSPArc) using an independent experimental approach.
- To investigate and quantify the treatment efficiency improvements offered by SPArc in routine proton clinical operations.
Main Methods:
- Generated and delivered SPArc test plans on an IBA ProteusONE prototype.
- Derived the DSMSPArc using an independent gantry inclinometer and machine logfiles.
- Validated the model's accuracy with 17 SPArc plans and assessed efficiency against Intensity Modulated Proton Therapy (IMPT) using clinical data.
Main Results:
- The DSMSPArc demonstrated high accuracy, with a 3.2 ± 4.8% difference compared to logfiles.
- SPArc reduced average patient treatment delivery time by 58.1% compared to IMPT (p < 0.01).
- A 30% increase in daily treatment throughput was observed with SPArc in a single-room proton therapy center.
Conclusions:
- The study established the first dynamic arc therapy model (DSMSPArc) through experimental validation.
- This model enables simulation of dynamic treatment delivery and assessment of throughput improvements for clinical users.
- SPArc offers significant potential for enhancing efficiency in proton therapy.
