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Risk factors for stroke outcomes in adults: Stroke in China

Rongli Fan1, Jingjie Gu1, Jingxin Zhang2

  • 1Zhejiang Provincial Key Laboratory for Chemical &Biological Processing Technology of Farm Products, Department of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou, Zhejiang, China.

Medicine
|December 8, 2023
PubMed

Insights

Lower Barthel Index scores and ischemic stroke increase the risk of poor stroke outcomes. This prospective study identified key factors influencing recovery in 146 Chinese stroke patients.

Area of Science:

  • Neurology
  • Clinical Research
  • Epidemiology

Background:

  • Stroke is a leading cause of long-term disability worldwide.
  • Identifying early risk factors for poor stroke outcomes is crucial for timely intervention.
  • Prognostic factors for stroke recovery vary across different populations.

Purpose of the Study:

  • To investigate the risk factors associated with poor stroke outcomes in a Chinese cohort.
  • To analyze demographic, clinical, and laboratory data to predict stroke prognosis.
  • To determine the predictive value of the Barthel Index and ischemic stroke on stroke outcomes.

Main Methods:

  • Prospective cohort study design involving 146 stroke patients in China.
  • Patients categorized into good (modified Rankin Scale [mRS] ≤ 2) and poor (mRS > 2) outcome groups at 90 days.
  • Multivariable logistic regression analysis to identify significant risk factors.

Main Results:

  • 19.18% of participants experienced poor stroke outcomes at 90 days.
  • A lower Barthel Index (BI) score was significantly associated with poor stroke outcomes (OR 1.50, P < .001).
  • Ischemic stroke (IS) was also a significant predictor of poor outcomes (OR 1.48, P < .001).

Conclusions:

  • Early assessment of Barthel Index and identification of ischemic stroke are vital for predicting stroke outcomes.
  • These findings can inform clinical management strategies to improve patient recovery.
  • Further research in diverse populations is warranted to validate these prognostic factors.

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