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Updated: Jul 9, 2025
A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies
Published on: July 28, 2020
Neoadjuvant Approaches to Non-Melanoma Skin Cancer
David C Wilde1, Mica E Glaun2, Michael K Wong3
1Bobby R. Alford Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, 1977 Butler Blvd. Suite E5.200, Houston, TX 77030, USA.
Abstract:
Surgery and external-beam radiation therapy are the primary treatment modalities for locally advanced NMSC, but they can lead to impairment of function and disfigurement in sensitive areas such as the head and neck. With the advent of targeted systemic therapies and immunotherapy, physicians have explored the ability to offer neoadjuvant therapy for NMSC in order to reduce surgically induced morbidity. Provided herein is a guide to current applications of neoadjuvant systemic therapies for NMSC and future directions.
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