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Homologous Recombination Deficiency Detection Algorithms: A Systematic Review

Lasse Ringsted Mark1,2, Simone Karlsson Terp1,2, Henrik Bygum Krarup1,2,3

  • 1Department of Molecular Diagnostics, Aalborg University Hospital, DK-9000 Aalborg, Denmark.

Cancers
|December 9, 2023
PubMed
Summary

Homologous recombination deficiency (HRD) testing is crucial for identifying patients who may benefit from PARP inhibitors. This review compares current HRD tests, highlighting the need for a standardized definition and approach for accurate clinical application.

Keywords:
HRDalgorithmbioinformaticscancerhomologous recombination deficiency

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