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Comorbid substance use disorder, major depression, and associated disability in a nationally representative sample
Vivian N Onaemo1, Batholomew Chireh2, Timothy O Fawehinmi3
1Division of Public Health and Preventive Medicine, Department of Community Health and Epidemiology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada; School of Public Health, University of Saskatchewan, 104 Clinic Place, Saskatoon, Saskatchewan S7N 2Z4, Canada.
Journal of Affective Disorders
|December 9, 2023
Summary
Individuals with both substance use disorders (SUDs) and major depressive episodes (MDE) face a significantly higher risk of disability. Integrated mental health and addiction services are crucial for improving outcomes.
Area of Science:
- Public Health
- Mental Health Research
- Addiction Medicine
Background:
- Major depressive disorders (MDD) and substance use disorders (SUDs) are leading causes of disability.
- Limited research exists on disability risk in individuals with comorbid MDD and SUDs within the general population.
Purpose of the Study:
- To investigate the risk of disability associated with comorbid SUDs and major depressive episodes (MDE).
- To analyze data from a nationally representative sample to understand these associations.
Main Methods:
- Utilized data from the 2012 Canadian Community Health Survey- Mental Health (CCHS-MH).
- Employed multilevel logistic regression models on a sample of 25,113 Canadians.
- Diagnoses based on DSM-IV criteria; disability assessed using WHO Disability Assessment Score (WHODAS) 2.0.
Main Results:
- Comorbidity of SUDs and MDE was the strongest predictor of disability.
- Individuals with comorbid SUDs and MDE were 4 to 9 times more likely to experience disability compared to those without either condition.
Conclusions:
- Comorbid SUDs and MDE significantly increase the risk of disability.
- Highlights the critical need for integrated mental health and addiction services to reduce disability and enhance treatment effectiveness.
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