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Updated: Jul 8, 2025

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Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
Published on: July 16, 2014
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Deep Brain Stimulation Improves Parkinson's Disease-Associated Pain by Decreasing Spinal Nociception
Veit Mylius1,2,3, Jan Harald Baars4, Karsten Witt5,6
1Department of Neurology, Center for Neurorehabilitation, Valens, Switzerland.
Abstract:
Dopamine exerts antinociceptive effects on pain in PD at cortical and spinal levels, whereas only cortical effects have been described for DBS, so far. By assessing the nociceptive flexion reflex (NFR) threshold at medication on, and DBS ON and OFF in two patients, we showed that DBS additionally decreases spinal nociception.

