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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
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Author Spotlight: Enhancement of Salient Object Detection for Smart Grid Applications
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Epidermis lesion detection via optimized distributed capsule neural network.

Vineet Kumar Dubey1, Vandana Dixit Kaushik1

  • 1Department of Computer Science & Engineering, Harcourt Butler Technical University, Kanpur, 208002, India.

Computers in Biology and Medicine
|December 10, 2023
PubMed
Summary
This summary is machine-generated.

A new Golden Hawk Optimization-based Distributed Capsule Neural Network (GHO-DCaNN) improves skin cancer detection accuracy. This method enhances early diagnosis of skin lesions, including melanoma, for better patient outcomes.

Keywords:
Distributed capsule neural networkEpidermis lesion detectionGolden hawk optimizationHybrid deep descriptorHybrid tetra pattern

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Computational Biology

Background:

  • Skin cancer, including melanoma, poses a significant global health risk, with early diagnosis critical for survival.
  • Accurate diagnosis of skin lesions remains challenging due to symptom complexity and variability.
  • Existing diagnostic methods require enhancement for improved accuracy and efficiency.

Purpose of the Study:

  • To introduce a novel computational approach for enhanced skin cancer detection.
  • To improve the accuracy and reliability of diagnosing skin lesions, particularly melanoma.
  • To develop an optimized deep learning model for precise epidermis lesion identification.

Main Methods:

  • A Golden Hawk Optimization-based Distributed Capsule Neural Network (GHO-DCaNN) was developed.
  • An optimized clustering-based segmentation approach using Sewer Shad Fly Optimization (SSFO) was integrated.
  • The GHO-DCaNN model was trained using a Hybrid GHO optimizer inspired by golden eagle and fire hawk behaviors.

Main Results:

  • The GHO-DCaNN achieved high performance metrics for skin lesion detection.
  • Specificity, sensitivity, and accuracy rates reached up to 97.53%, 99.05%, and 98.83% with 90% training data.
  • With 10-fold cross-validation, performance improved to 97.83% specificity, 99.50% sensitivity, and 99.06% accuracy.

Conclusions:

  • The proposed GHO-DCaNN demonstrates significant potential for accurate and efficient skin cancer diagnosis.
  • The integration of advanced optimization algorithms enhances lesion segmentation and feature extraction.
  • This computational approach offers a promising advancement in the field of medical imaging for dermatology.