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Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors
Published on: September 13, 2018
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Arboviruses: Transmission and Host Resistance
Sidra Anwar1, Bilal Ahmed2, Muhammad Imran Qadir3
1Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, Multan, Pakistan.
Critical Reviews in Eukaryotic Gene Expression
|December 11, 2023
Summary
This review details arboviruses, their evolution, transmission by vectors like mosquitoes and ticks, and host resistance mechanisms including RNA interference (RNAi). It covers prevention strategies against these significant viral threats.
Area of Science:
- Virology
- Epidemiology
- Vector-borne Diseases
Background:
- Arboviruses represent a diverse group of viruses transmitted by arthropod vectors.
- Understanding arbovirus evolution, characterization, and transmission is crucial for public health.
- Host-vector interactions and resistance mechanisms are key to controlling viral spread.
Approach:
- This review provides a comprehensive overview of arbovirus classification and evolutionary pathways.
- It details various disease transmission methods, including biological and non-biological routes.
- The review examines host resistance mechanisms and artificial prevention technologies.
Key Points:
- Vectors such as mosquitoes and ticks play a vital role in arbovirus transmission.
- Host resistance mechanisms, like RNA interference (RNAi), combat viral replication.
- Artificial methods, including repellents and Insect Growth Regulators (IGRs), aid in prevention.
Conclusions:
- Arboviruses pose significant challenges due to their complex transmission cycles.
- Effective control requires a multi-faceted approach targeting vectors, hosts, and viral agents.
- Continued research into host-pathogen interactions and novel prevention technologies is essential.
