[Long-term sequelae of splenic loss]

Beside the increased risk of infection there are further long lasting consequences of splenectomy. The hematologic changes include morphological alterations of red cells, lymphocytosis, monocytosis and increased blood viscosity. There are complaints about general disturbances like physical weakness, abdominal pain or intolerance of alcohol. The response to certain vaccinations is impaired especially in the early postoperative period. Findings concerning the influence on the growth of cancer are controversial. There seems to be an increased risk of disturbed wound healing.