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Updated: Jul 8, 2025

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Published on: May 2, 2025
An extension of cancer immunotherapy with dostarlimab, the PD1-PD L1 pathway blocker
Sitangshu Sekhar Biswas1, Sarath BabuV2, Abhipsa Chakraborty3
1Independent Researcher,SRMIST, Chennai, India.
Abstract:
Cancer immunotherapy is a treatment that uses the body's own immune system to fight against cancer. Malignant cells in the human body have the ability to mutate themselves in such a way that they can escape from immune system surveillance and proliferate. So, if the human immune system could be boosted or its surveillance and defensive mechanisms improved so that our bodies can detect cancer cells and kill them by combining all of the human body's defensive mechanisms, it would be much easier to deal with cancer. A recent trial at Memorial Sloan Kettering Cancer Center in New York found that by using a drug called Dostarlimab, rectal adenocarcinoma could be cured by boosting the human immune system to detect and kill cancer cells. This could be considered a validated extension of cancer immunotherapy. This paper will explain how dostarlimab works on the body's immune system and destroys cancer cells in a simple way that anyone who is not in the medical field also can understand.
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