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Donor Evaluation Protocol for Live and Deceased Donors
Pankaj Puri1, Abhinav Kumar1, Mohd Qaleem2
1Fortis Escorts Liver and Digestive Diseases Institute, Fortis Escorts Hospital, New Delhi-110025, India.
Journal of Clinical and Experimental Hepatology
|December 11, 2023
Summary
Evaluating liver transplant donors is crucial for successful outcomes. This review covers essential factors for both living and deceased donors, including graft health and safety, to optimize transplantation success.
Area of Science:
- Transplantation Medicine
- Hepatology
- Surgical Research
Background:
- Liver transplantation (LT) success hinges on meticulous donor selection.
- Increasing use of extended-criteria or 'marginal donors' necessitates careful evaluation.
- Living donor liver transplantation (LDLT) requires prioritizing donor safety.
Purpose of the Study:
- To review critical factors in donor evaluation for liver transplantation.
- To address considerations for both deceased donor LT (DDLT) and LDLT.
- To emphasize the importance of graft quality and donor safety.
Main Methods:
- Literature review of current practices in donor evaluation for LT.
- Analysis of factors influencing graft viability and recipient outcomes.
- Examination of risks associated with donor selection, including infection and malignancy transmission.
Main Results:
- Donor evaluation is paramount for successful LT outcomes.
- Graft health and the absence of transmitted diseases are key selection criteria.
- Balancing organ scarcity with donor safety is essential, especially with marginal donors.
Conclusions:
- Comprehensive donor evaluation is vital for optimizing liver transplant success.
- Adherence to donor safety protocols is critical in LDLT.
- Careful consideration of donor factors improves graft survival and patient prognosis.
