Related Experiment Video
Updated: Jul 8, 2025
07:14
A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
Published on: January 18, 2018
9.4K
Perioperative Pain Management and Cancer Outcomes: A Narrative Review
Maria F Ramirez1, Amanda Strang2, Gavin Roland2
1Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Journal of Pain Research
|December 11, 2023
Summary
Effective cancer pain management uses a tailored perioperative approach. Opioids are crucial for severe pain, but their role is evolving due to misuse concerns and ongoing research into cancer recurrence.
Area of Science:
- Oncology
- Anesthesiology
- Pain Management
Background:
- Cancer-related pain is a prevalent and debilitating symptom impacting patient quality of life and function.
- Pain can stem from cancer itself, diagnostic/therapeutic procedures, or treatment side effects.
- Optimal perioperative pain control necessitates individualized strategies.
Purpose of the Study:
- To review pharmacological management of acute cancer pain in the perioperative setting.
- To emphasize the impact of pain management on cancer recurrence.
- To discuss the evolving role of opioids in cancer pain treatment.
Main Methods:
- Literature review of pharmacological interventions for acute perioperative cancer pain.
- Analysis of current treatment guidelines and research findings.
- Focus on agents including regional anesthesia, local anesthetics, non-opioid analgesics, and opioids.
Main Results:
- A multimodal approach combining regional anesthesia, non-opioid analgesics (ketamine, dexmedetomidine, lidocaine, NSAIDs), and opioids is recommended.
- Opioids remain essential for moderate to severe cancer pain, despite concerns regarding the opioid epidemic.
- Evidence linking opioid use to negative cancer outcomes is inconclusive from randomized controlled trials.
Conclusions:
- Perioperative pain management requires a personalized strategy.
- The use of opioids for cancer pain is under scrutiny due to misuse, necessitating careful consideration.
- Further research is needed to clarify the relationship between perioperative opioid use and cancer recurrence.
Related Concept Videos
01:21Cancer Survival Analysis
355
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
355
01:25Analgesia and Pain Management
628
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
628
02:49Cancer Therapies
7.7K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.7K
01:26Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
88
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
88
01:24General Anesthesia: Overview
223
Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
223
01:11Guidelines for Writing Outcome
2.8K
When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
2.8K